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What is Melanoma? Melanoma is a tumor of melanocytes, the pigment-producing cells that give our skin its color. These cells are located all over the skin, but are more heavily concentrated in moles. When one of these cells becomes malignant it produces a tumor called a melanoma. A melanoma may appear in a mole that has been present for a long time or in parts of the skin which previously appeared normal. Read more about what Melanoma is, what causes it, how it's treated, etc, by visiting the links below.
. Latest News on Melanoma: New Treatments for Melanoma: - Strategies for Combining Chemotherapy and Biotherapy in Melanoma -
The treatment of metastatic melanoma remains unsatisfactory, with patient survival dictated primarily by the pace of the disease. Of all the currently employed treatment modalities, cisplatin-based regimens combined with biologic agents such as interferon alfa (IFN-a) and interleukin-2 (IL-2), referred to as "biochemotherapy"or "chemoimmunotherapy," have attained the highest clinical response. Read more at: http://www.mpip.org/topframeset.shtml?articles/chemostrategies.pdf (Requires Adobe Reader)
. - FDA Grants Fast-Track Designation To G-3139 For Malignant Melanoma -
The U.S. FDA granted fast-track designation to the bcl-2 antisense compound, G-3139, for use in combination with dacarbazine for treatment of advanced malignant melanoma. This drug is in phase I-II trials for malignant melanoma and is in 7 other clinical trials for other patients with lymphoma and solid tumors, such as small cell lung cancer, colorectal cancer and acute leukemia. Read all about it at: http://www.pslgroup.com/dg/13fc2a.htm
. - FDA Grants Orphan Drug Designation To Allovectin-7 For Melanoma Treatment -
Allovectin-7 has been granted orphan drug designation in the U.S. for treatment of invasive and metastatic melanoma. Melanoma is a skin cancer with exposure to sunlight and the UV B rays being considered the primary cause of the cancer. The incidence of melanoma has been doubling every 6 - 10 years here in the US with 44 000 new cases in the US during 1999 alone. Allovectin-7 uses a lipid-DNA complex to help the immune system recognize and attack cancer cells. It is currently in Phase II and Phase III testing in certain patients with metastatic melanoma and in Phase II testing in patients with unresectable head and neck cancer. Leading cancer centers throughout the United States are recruiting patients with metastatic melanoma for Phase III and Phase II registration trials with Allovectin-7. Read all about it at: http://www.pslgroup.com/dg/13f7de.htm
. - Temozolomide Holds Promise For Advanced Metastatic Melanoma -
Temozolomide, a recently approved oral treatment for brain cancer, as been shown to be at least as effective as DTIC, a current standard treatment, against advanced metastatic melanoma, a study shows.the study was reported in the January edition of the Journal of Clinical OncologyRead all about it at above URL.
. URL sites on the Web on Malignant Melanoma
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