| Awards - 2008 | | |
| Nomination | Teen Choice Award | Juno |
| | Choice Movie Actress Comedy | |
| Nomination | Teen Choice Award | Juno |
| | Choice Movie Breakout Female | |
| Winner | MTV Movie Awards | Juno |
| | Best Female Performance | |
| Nomination | MTV Movie Awards | Juno |
| | Best Kiss | |
| Winner | NewNowNext Awards (Audience Choice) | |
| | Brink of Fame: Actor | |
| Nomination | ACTRA Award | The Tracey Fragments |
| | Best Performance - Female | |
| Winner | Film Independent's Spirit Award | Juno |
| | Best Female Lead | |
| Winner | Vancouver Film Critics Circle Awards | The Tracey Fragments |
| | Best Actress in a Canadian Film | |
| Nomination | Genie Award | The Tracey Fragments |
| | Best Actress | |
| Nomination | Oscar (Academy Award) | Juno |
| | Best Actress in a Leading Role | |
| Winner | Talented Young Person of the Month Award | |
| Nomination | BAFTA Award | Juno |
| | Best Actress | |
| Nomination | BAFTA Award | Juno |
| | Orange Rising Star Award | |
| Nomination | Golden Globe | Juno |
| | Best Actress in a motion picture - Comedy or Musical | |
| Nomination | Screen Actors Guild Award | Juno |
| | Female actor in a leading role | |
| Nomination | Critics' Choice Awards | Juno |
| | Best Actress | |
| Winner | Santa Barbara Virtuosos Award | Juno |
| Winner | Central Ohio Film Critics Association Award | Juno |
| | Best Actress |
