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What are the possible side effects of lorazepam? • If you experience any of the following serious side effects, stop taking lorazepam and seek emergency medical attention or contact your doctor immediately: • an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, face, or tongue; or hives); • sores in the mouth or throat; • yellowing of the skin or eyes; • a rash; • hallucinations or severe confusion; or • changes in vision

• Other, less serious side effects may be more likely to occur

Continue to take lorazepam and talk to your doctor if you experience • drowsiness, dizziness, or clumsiness; • depression; • nausea, vomiting, diarrhea, or constipation; • difficulty urinating; • vivid dreams; • headache; • dry mouth; • decreased sex drive; or • changes in behavior

• Side effects other than those listed here may also occur

Talk to your doctor about any side effect that seems unusual or that is especially bothersome

What other drugs will affect lorazepam? • Lorazepam may increase the effects of other drugs that cause drowsiness, including antidepressants, alcohol, antihistamines, sedatives (used to treat insomnia), pain relievers, anxiety medicines, seizure medicines, and muscle relaxants

Tell your doctor about all medicines that you are taking, and do not take any medicine without first talking to your doctor

• Antacids may decrease the effects of lorazepam

Separate doses of an antacid and lorazepam by several hours whenever possible

• Drugs other than those listed here may also interact with lorazepam

Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines, including vitamins, minerals, and herbal products

Ativan (benzodiazepines) Definition Sedative-hypnotics are Central Nervous System (CNS) depressants and are a category of drugs that slow normal brain function

There are numerous CNS depressants; most act on the brain by affecting the neurotransmitter gamma-aminobutyric acid (GABA)

Neurotransmitters are brain chemicals that facilitate communication between brain cells

GABA works by decreasing brain activity

Although the different classes of CNS depressants work in unique ways, ultimately it is through their ability to increase GABA activity that they produce a drowsy or calming effect that is beneficial to those suffering from anxiety or sleep disorders

Among the medications that are commonly prescribed for these purposes are the following: Benzodiazepines (ativan), such as diazepam (Valium), chlordiazepoxide HCl (Librium), and alprazolam (Xanax), which can be prescribed to treat anxiety, acute stress reactions, and panic attacks; the more sedating benzodiazepines, such as triazolam (Halcion) and estazolam (ProSom) can be prescribed for short-term treatment of sleep disorders

In higher doses, some CNS depressants can be used as general anesthetics