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| Definition: Periodontal disease is marked by inflammatory injuries (called lesions) from calculus, a hard substance that forms from plaque, which is essentially bacterial overgrowth. Bacterial proliferation, however, is not the end of the story. A persistent immune response to this chronic infections is now believed to play a major role in not only destruction in the gums but in other parts of the body as well. | I have been looking into the chemical I suspect for many if not most autoimmune disorders: diabetes, the CFIDS issues ... it is a LARGE web! ... (CFIDS &/or diabetes would show up first, the Yeast Infections and periodontal disease as more exposure to this chemical .... a more strongly autoimmune system - then various cancers & tumors should show up - my theory WWII Vets health AND children) ... Should show up for many 'baby boomers' like me So I looked up periodontal disease, autoimmune? and found .... Evidence now suggests that periodontal disease is an autoimmune disorder, in which immune factors in the body attack the person's own cells and tissue -- in ... The Autoimmune and Inflammatory Response Evidence now suggests that periodontal disease is an autoimmune disorder, in which immune factors in the body attack the person's own cells and tissue -- in this case, those in the gum. It appears to work as follows: - The bacteria that form plaque and tartar release toxins that stimulate the immune system to overproduce powerful infection-fighting factors called cytokines.
- Ordinarily, cytokines are important for healing. In excess, however, they can cause inflammation and severe damage. Cytokines of particular importance in periodontal disease are known as tumor necrosis factor-alpha (TNF-alpha) and interleukin-1beta, which are very active in the mouth, and are important in causing destructive inflammation.
- In addition, white blood cells produced by the immune response to bacteria also release a family of enzymes called matrix metalloproteinases (MMPs), which break down connective tissue.
Studies suggest that this inflammatory response may have damaging effects not only in the gums but also in organs throughout the body, include the heart. (Source: about.com adam.about.com/reports/000024_2.htm) Original source, March, 2002: Periodontal Disease - Evidence now suggests that periodontal disease may be an autoimmune disorder, in which immune factors in the body attack the person's own cells and tissue--in this case, those in the gum. www.reutershealth.com/wellconnected/doc24.html _______________________________ Multiple & many exposures to 2-butoxyethanol type chemical/s can also lead to ALS (my opinion) ... or many things along the way ... Diabetes? Diabetes itself may be one of the Birth Defects of a parents' exposure to 2-butoxyethanol .... ______________________ Good discussion on periodontal disease: http://forum.lef.org/default.aspx?f=41&m=16360 Fair Use | Web page * Bev Anne shares about teeth concerns after CFS & autoimmune diagnosis * 3-30-07 repost
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